Heather McCann
Manager, Sydney Brain Bank
Current Appointments
Director Sydney Brain BankDr Claire Shepherd is the Director of the Sydney Brain Bank at Neuroscience Research Australia. She trained in neuroscience and completed her PhD in Alzheimers disease at the University of Sheffield, UK. After completing her PhD she relocated to Sydney to pursue her interest in the neuropathology of dementia. Soon after her move, Claire was awarded the prestigious Rolf Edgar Lake Fellowship from the University of Sydney and subsequently directed a National Health and Medical Research Council (NHMRC) project grant as CIA. In 2000 Claire was awarded the inaugural Franz Nissl Young Investigator Prize in Neuroscience in recognition of achievements in her early post-doctoral years. She now runs the Sydney Brain Bank, which is a research facility that collects, characterises and stores brain tissue for research into neurodegenerative disease. Claire is also the Director of the Shepherd Dementia Research Laboratory at NeuRA and lead investigator on the NeuRA Volunteers Brain Donor Program a longitudinal research program aimed at investigating the clinical consequences of the cellular changes that occur during ageing. In October 2019, Claire received funding from the Brain Foundation for a new research program that will investigate the presence of chronic traumatic encephalopathy (CTE) in the brain tissue of a large population of well-characterised individuals held by the Sydney Brain Bank and determine any association with repetitive traumatic brain injury exposure. On 27 November, the National Rugby League (NRL) announced support of a Newcastle University-based research program for former players. The participants in this program will be invited to donate their brains to the Sydney Brain Bank after death to facilitate medical research. This is part of Claire's newest research into how sports-related brain changes impact on a players quality of life.
2024, 01 Dec
Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA
View full journal-article on https://app.dimensions.ai/details/publication/pub.1176007381
2024, 01 Sep
Poly-GA immunohistochemistry is a reliable tool for detecting C9orf72 hexanucleotide repeat expansions
View full journal-article on https://app.dimensions.ai/details/publication/pub.1164846308
2024 Apr
Chronic traumatic encephalopathy neuropathologic change in former Australian rugby players
View full journal-article on https://doi.org/10.1111/nan.12972
2024 Feb
GBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians.
View full journal-article on http://europepmc.org/abstract/med/38390630
2024, 01 Jan
Is SH3GL2 p.G276V the Causal Functional Variant Underlying Parkinson's Disease Risk at this Locus?
View full journal-article on https://app.dimensions.ai/details/publication/pub.1174681381
2024, 01 Jan
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
View full journal-article on https://app.dimensions.ai/details/publication/pub.1167389368
2023, 01 Dec
Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2) (npj Parkinson's Disease, (2023), 9, 1, (100), 10.1038/s41531-023-00526-9)
View full journal-article on https://app.dimensions.ai/details/publication/pub.1164031892
2023, 01 Dec
Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)
View full journal-article on https://app.dimensions.ai/details/publication/pub.1164024681
2023, 01 Dec
Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis
View full journal-article on https://app.dimensions.ai/details/publication/pub.1165911804
2023, 01 Nov
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study
View full journal-article on https://app.dimensions.ai/details/publication/pub.1163494217
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