We hope to deepen our understanding of this complex disease in order to find more effective pathways to prevention and treatment.
Mitochondrial disease is a type of genetic disorder that affects the mitochondria, which are the part of the cell that is responsible for producing energy. This type of disease can affect many different parts of the body, including the brain, muscles, and other organs. The core dynamic driving Mitochondrial disease (as well as Parkinson’s disease) is that brain cells cannot generate sufficient energy. Through research, our goal is to improve that function and slow the process of degeneration.
While Mitochondrial disease and Parkinson's disease are not the same condition, they are related in that both conditions can affect the mitochondria. Our research is looking at ways to provide a renewable source of energy in cells by overexpressing a protein which improves energy production. By doing this, we are hopeful that both patients with Mitochondrial disease and Parkinson’s disease will benefit.
Kinghorn Chair, Neurodegeneration
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