Hayley North
Postdoctoral Fellow
Learn more about Hayley
Professor
Cyndi Shannon Weickert
Current Appointments
NSW Chair of Schizophrenia Research
Professor, School of Psychiatry, UNSW
Professor, Department of Neuroscience and Physiology, Upstate Medical University, New York
Key Research Areas
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Cyndi’s research is focused on the molecular developmental neurobiology of schizophrenia. She earned a PhD in Biomedical Science at Mount Sinai School of Medicine, New York City and completed postdoctoral training at the National Institute of Mental Health rising to the level of Unit Chief of Molecules in the Neurobiology and Development of Schizophrenia Unit. Her awards include the Eli Lilly Young Investigator Award, NIH Fellows Award for Research Excellence, Independent Investigator Award and two Young Investigator Awards from NARSD. She has lectured throughout the world and contributed to over 150 publications.
My research has several aims:
- To determine the neurobiological underpinning of psychiatric diseases in order to develop more effective treatments.
- To identify biological subgroups of people with schizophrenia based on inflammation. Â To determine if these subgroups cut across schizophrenia, bipolar and depression.
- To use knowledge gained on neuroinflammation subgroups in major psychiatric disorders to inform the development of biologically informed treatments (or more individualised treatments).
- To understand how the balance between factors that damage brain cells verses factors that repair and regenerate brain cells differ in psychiatric conditions.
Publications
2024 Oct
Molecular Evidence for Altered Angiogenesis in Neuroinflammation-Associated Schizophrenia and Bipolar Disorder Implicate an Abnormal Midbrain Blood-Brain Barrier.
View full journal-article on http://europepmc.org/abstract/med/39471484
2024 Oct
Schizophrenia-associated changes in neuronal subpopulations in the human midbrain.
View full journal-article on http://europepmc.org/abstract/med/39397771
2024 Sep
Transcriptional evidence of reduced BDNF trophic signalling capacity in the post-mortem human midbrain of schizophrenia cases with high inflammation
View full preprint on http://europepmc.org/abstract/PPR/PPR905530
2024 Aug
Increased Parenchymal Macrophages are associated with decreased Tyrosine Hydroxylase mRNA levels in the Substantia Nigra of people with Schizophrenia and Bipolar Disorder.
View full journal-article on http://europepmc.org/abstract/med/39153291
2024 Jul
Antipsychotic-induced prolactin elevation in premenopausal women with schizophrenia: associations with estrogen, disease severity and cognition.
View full journal-article on http://europepmc.org/abstract/med/38995314
2024 Jul
Molecular evidence of altered stress responsivity related to neuroinflammation in the schizophrenia midbrain.
View full journal-article on http://europepmc.org/abstract/med/39004003
2024 Jun
The association of prolactin and gonadal hormones with cognition and symptoms in men with schizophrenia spectrum disorder: Divergent effects of testosterone and estrogen.
View full journal-article on http://europepmc.org/abstract/med/38944973
2024 May
RNA-sequencing suggests extracellular matrix and vasculature dysregulation could impair neurogenesis in schizophrenia cases with elevated inflammation.
View full journal-article on http://europepmc.org/abstract/med/38704390
2024 Mar
Single-Nucleus RNA-Seq Characterizes the Cell Types Along the Neuronal Lineage in the Adult Human Subependymal Zone and Reveals Reduced Oligodendrocyte Progenitor Abundance with Age.
View full journal-article on http://europepmc.org/abstract/med/38351133
2024 Mar
Toll-Like Receptor mRNA Levels in Schizophrenia: Association With Complement Factors and Cingulate Gyrus Cortical Thinning.
View full journal-article on http://europepmc.org/abstract/med/38102721
Cyndi's research team
Cyndi's research projects and related news
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