Professor Simon Gandevia
Deputy Director and Foundation Scientist, NeuRA
Motor Impairment is the final pathway that causes physical disability in a wide range of diseases and health conditions. It can involve weakness, fatigue, impaired sensation, reduced balance, muscle contracture and poor co-ordination - common features of many health conditions and ageing.
NeuRA has a strong history of multidisciplinary research and leadership in advancing scientific understanding of the mechanisms and impacts of motor impairment. In addition to our world-leading spinal cord injury research, a key current focus is the issue of contracture: the disabling stiffening of muscles that occurs after a range of brain lesions such as stroke, head injury, spinal cord injury and cerebral palsy.
By improving clinical interventions designed to prevent and reverse muscle contractures, we hope to transform the lives of thousands of Australians with cerebral palsy, muscular dystrophy, rheumatoid arthritis and stroke.
Why Does Quadriceps Weakness Persist after Total Knee Replacement?An Exploration of Neurophysiological MechanismsTotal knee replacement is a commonly performed surgery for treating end-staged knee osteoarthritis. Although most people recover well after surgery,…
Osteoarthritis affects more than 20% of Australians aged over 60. The knee joint is commonly affected, causing persistent pain and difficulty in daily activities. Although exercise is the cornerstone of conservative treatment for knee osteoarthritis and recommended in…
The MUGgLE study is a research study on growth of muscles and tendons during childhood development. We are studying muscles of typically developing children and of children with cerebral palsy using MRI scans of the lower legs.The MUGgLE study is a collaboration…
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