Sicong Tu

Current Appointments

Lenity Senior Research Fellow (USYD)

Honorary Appointment (NeuRA)

Key Research Areas

Motor Neurone Disease and Frontotemporal Dementia

Motor neurone disease

Frontotemporal dementia

Dementia

Alzheimer's disease

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Dr Sicong Tu is the Lenity Senior Research Fellow for neurodegenerative disorders at the Brain and Mind Centre, University of Sydney. His research employs leading multi-modal neuroimaging techniques (structural/functional/metabolic) to quantify changes in brain integrity and connectivity associated with neurodegeneration and cognitive dysfunction.

His research focuses on the discovery and translation of novel non-invasive markers for monitoring and tracking disease progression from its earliest stage in dementia and motor neuron disease. He holds particular interest in characterising regional patterns of change across key neural relay hubs as a marker of widespread cortical dysfunction and brain network abnormality.

Publications

2024, 10 Dec

An Annotated Multi-Site and Multi-Contrast Magnetic Resonance Imaging Dataset for the study of the Human Tongue Musculature

View full preprint on https://doi.org/10.1101/2024.12.09.24318591

2024, 04 Jul

Pathological insights derived from neuroimaging in amyotrophic lateral sclerosis: emerging clinical applications.

View full journal-article on https://doi.org/10.1097/WCO.0000000000001295

2024 Jul

Novel approaches to assessing upper motor neuron dysfunction in motor neuron disease/amyotrophic lateral sclerosis: IFCN handbook chapter

View full journal-article on https://doi.org/10.1016/j.clinph.2024.04.010

2022, 02 Nov

Progress, development, and challenges in amyotrophic lateral sclerosis clinical trials

View full journal-article on https://doi.org/10.1080/14737175.2022.2161893

2022, 13 Mar

Schizotypal traits across the amyotrophic lateral sclerosis-frontotemporal dementia spectrum: pathomechanistic insights.

View full journal-article on https://doi.org/10.1007/s00415-022-11049-3

2022, 01 Mar

Thalamic and Cerebellar Regional Involvement across the ALS–FTD Spectrum and the Effect of C9orf72

View full journal-article on https://doi.org/10.3390/brainsci12030336

2021, 27 Dec

A robust framework for characterising diffusion metrics of the median and ulnar nerves: Exploiting state-of-the-art tracking methods.

View full journal-article on https://doi.org/10.1111/jns.12478

2021 Dec

Apathy is associated with parietal cortical-subcortical dysfunction in ALS

View full journal-article on https://doi.org/10.1016/j.cortex.2021.02.029

2021, 23 Oct

Tackling clinical heterogeneity across the amyotrophic lateral sclerosis-frontotemporal dementia spectrum using a transdiagnostic approach.

View full journal-article on https://europepmc.org/articles/PMC8599039

2021, 08 Jul

Brainstem Correlates of Pathological Laughter and Crying Frequency in ALS.

View full journal-article on https://europepmc.org/articles/PMC8296641

View all publications

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