Current AppointmentsPrincipal Research Scientist
Key Research Areas
Jan completed her PhD in human genetics at The University of Melbourne in 2001. She then spent five years as a postdoctoral researcher at The Wellcome Trust Centre for Human Genetics, University of Oxford (UK), where she developed her career interest in psychiatric genetics and complex trait analysis, studying the genetic contributors to personality, depression and anxiety in both humans and mice. She returned to Australia in 2006 on a NHMRC Howard Florey Fellowship, which allowed her to join the institute to study the genetics of bipolar disorder and schizophrenia. In 2013, Jan was promoted to Research Fellow and Group Leader, where she heads a number of projects in both gene discovery, and examining the role of specific genes in risk of major psychiatric conditions.
2023, 14 Feb
Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder
View full preprint on https://doi.org/10.21203/rs.3.rs-2580252/v1
Wellbeing and brain structure: A comprehensive phenotypic and genetic study of image‐derived phenotypes in the UK Biobank
View full journal-article on https://doi.org/10.1002/hbm.25993
Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM.
View full journal-article on http://europepmc.org/abstract/med/35505515
2022, 04 Apr
Genetic and environment effects on structural neuroimaging endophenotype for bipolar disorder: a novel molecular approach
View full journal-article on https://doi.org/10.1038/s41398-022-01892-3
Genetic variants associated with longitudinal changes in brain structure across the lifespan.
View full journal-article on http://europepmc.org/abstract/med/35383335
2022, 19 Mar
Phenotypic and genetic analysis of a wellbeing factor score in the UK Biobank and the impact of childhood maltreatment and psychiatric illness
View full journal-article on https://doi.org/10.1038/s41398-022-01874-5
Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative.
View full journal-article on http://europepmc.org/abstract/med/35322518
Virtual Ontogeny of Cortical Growth Preceding Mental Illness.
View full journal-article on http://europepmc.org/abstract/med/35489875
Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses.
View full journal-article on http://europepmc.org/abstract/med/35146571
Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach.
View full journal-article on http://europepmc.org/abstract/med/35225756
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