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Dr

Anita Nitchingham

MBBS, FRACP, PhD


Current Appointments

Conjoint, NeuRA
Geriatrician, Prince of Wales Hospital Conjoint Lecturer, University of New South Wales
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Dr Anita Nitchingham is a geriatrician and clinician-researcher whose work focuses on improving outcomes for older people with delirium. Her research spans the neurobiology of delirium, clinical trials, implementation science and the interface between delirium and dementia.

Anita completed her PhD through UNSW and NeuRA, investigating the biological mechanisms underlying delirium using advanced neuroimaging. Her work demonstrated regional cerebral hypometabolism during delirium, independent of acute illness and dementia, helping to advance understanding of the brain changes that occur during acute cognitive disturbance. She has also led the world’s first randomised controlled trial of intranasal insulin for the treatment of established delirium, evaluating a novel mechanistically targeted therapy in hospitalised older adults.

 Her current research focuses on the long-term consequences of delirium, including cognitive decline, functional recovery and dementia risk after hospitalisation. She leads translational projects at Prince of Wales Hospital developing post-discharge delirium recovery pathways, with a focus on early identification of ongoing cognitive concerns, rehabilitation, patient and carer education, and connection with appropriate services. Her work aims to integrate clinical assessments with blood-based biomarkers to better understand why some patients recover after delirium while others experience persistent decline.

Anita is Vice-President of the Australasian Delirium Association and contributes to national and international collaborations in delirium research and education. Her broader goal is to build evidence-based models of care that recognise delirium as a major brain health event and improve recovery, independence and quality of life for older people and their families.


Publications

2026

PHARMACOLOGICAL MANAGEMENT OF DELIRIUM: CURRENT PRACTICE AND EMERGING THERAPEUTIC TARGETS-A GERIATRICIAN'S PERSPECTIVE

2025

Cerebral metabolic covariance in delirium: pattern response to symptomatic changes

2025

Long-acting intranasal insulin for the treatment of delirium-a randomised clinical trial

2023

Regional cerebral hypometabolism on 18F-FDG PET/CT scan in delirium is independent of acute illness and dementia

2023

Statistical Analysis Plan of Intranasal Insulin for Treatment of Delirium in Older Hospitalised Patients

2022, 09 Aug

Persistent delirium in older hospital patients: an updated systematic review and meta-analysis

View full journal-article on https://doi.org/10.56392/001c.36822

2022

Persistent delirium in older hospital patients: an updated systematic review and meta-analysis

2021

Current Challenges in the Recognition and Management of Delirium Superimposed on Dementia

2021

Delirium in older adults is associated with development of new dementia: a systematic review and meta-analysis

2021

Intranasal insulin for treatment of delirium in older hospitalised patients: study protocol for a randomised controlled trial


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